It happened last night, in the new episode entitled The Miseducation of Lisa Simpson.
After the two mentions in the 90s and 00s (you can view them here), Pearl Jam were mentioned again in the Simpsons last night.
You can watch the full episode on Fox via their website.
I wanna breathe, follow the scene
I wanna taste everyone I see, I wanna run, when I’m up high
I wanna ride into the sea, I only want life to be
I just wanna be, I will feel alive as long as I am free
Favorite song: Rearviewmirror
Favorite album: Vs.
Favorite bands/artists other than PJ: The Beatles, The Who, Queen, Soundgarden, Jeff Buckley